In vitro pituitary and thyroid cell proliferation assays and their relevance as alternatives to animal testing
نویسندگان
چکیده
منابع مشابه
In vitro pituitary and thyroid cell proliferation assays and their relevance as alternatives to animal testing.
This study investigates the in vitro effect of eleven thyroid-active compounds known to affect pituitary and/or thyroid weights in vivo, using the proliferation of GH3 rat pituitary cells in the so-called "T-screen," and of FRTL-5 rat thyroid cells in a newly developed test denoted "TSH-screen" to gain insight into the relative value of these in vitro proliferation tests for an integrated testi...
متن کاملAlternatives in animal testing.
1Division of Hematology/Oncology, Department of Medicine, Health Science Center, University of Florida, P.O. Box 100277, Gainesville, FL 32610, USA 2Division of Cardiology, Department of Medicine, Health Science Center, University of Florida, P.O. Box 100277, Gainesville, FL 32610, USA 3Department of Pathology, Health Science Center, University of Florida, P.O. Box 100277, Gainesville, FL 32610...
متن کاملin translation: translators on their work and what it means
کتاب در باب ترجمه، اثر استر آلن و سوزان برنوفسکی منتشر شده در ماه می 2013 توسط نشریه کلمبیا است. نویسندگان در این کتاب به بررسی 18 مترجم با در نظر گرفتن نقش آثاری که این مترجمان ترجمه کرده اند میپردازند. کتاب به دو بخش تقسیم میشود: " مترجم در جهان" و " کار مترجم" این دو بخش مقالات همیشگی ترجمه و موقعیت خاص ادبیات بیگانه در جهان وسیع امروزی را مورد خطاب قرار میدهد. در این کتاب مقالات متعددی از ن...
Development and use of in vitro alternatives to animal testing by the pharmaceutical industry 1980–2013
We examined the use of in vitro (including in silico) techniques in preclinical safety testing by the pharmaceutical industry between 1980 and 2013 to determine patterns, drivers and challenges in uptake. Data were collected via a survey sent to the Association of the British Pharmaceutical Industry (ABPI) member companies from the Nonclinical and Biological Discovery Expert Network (NaBDEN) re...
متن کاملAlternatives to animal testing: A review.
The number of animals used in research has increased with the advancement of research and development in medical technology. Every year, millions of experimental animals are used all over the world. The pain, distress and death experienced by the animals during scientific experiments have been a debating issue for a long time. Besides the major concern of ethics, there are few more disadvantage...
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ژورنال
عنوان ژورنال: ALTEX
سال: 2013
ISSN: 1868-596X
DOI: 10.14573/altex.2013.3.293